| Parvovirus B19 - found associated with: |
Parvovirus B19 - possibly associated with: |
• Erythema infectiosum (fifth disease)*
• Cytopenias:
Aplastic anemia
Erythroblastosis
Dyserythropoiesis
Leukoerythroblastosis
Neutropenia
Trombocytopenia
•Neurologic complications:
Encephalitis
Hemiconvulsion-
hemoplegia-epilepsy syndrome
Chorea encephalopathy
Neuropathy
Frontal lobe seizures
Neuralgic amytrophy
• Myocarditis
• Dilated cardiomyopathy
• Pericarditis
• Arthritis
• Arthropathie
• Myositis
• Dermatomyositis
• Glomerulonephritis
• Hepatitis
• SLE
• Multisystem vasculitis
• Hashimoto's thyroiditis
• Uveitis
• Optic neuritis
• Conjunctivitis
• Haemophagocytic lymphohistiocytosis
• Haemophagocytic syndrome
• Velopharyngeal insufficience
• Wells syndrome
• Adult Reye-like syndrome
• Papular purpuric gloves and socks syndrome
• Purpuric or petechial rashes
• Gianotti-Crosti syndrome (GCS)
• Hepatosplenomegaly
• Ophtalmoparesis
• Red baby syndrome
• HUS-like episodes (hematuria, proteinuria)
• Acute respiratory distress syndrome
• Henoch-Schonlein
• Swachman-Diamond syndrome |
• Erythema nodosum
• Granulomatous disease
• Kawasaki
• Stroke
• Diabetis mellitus type 1
• Testicular germ cell tumours |
| Parvovirus B19 - children with higher risk of more severe disease states (in particular cytopenias) |
• Spherocytosis
• Immunodeficiences ( congenital acquired, HIV)
• Sickle cell anaemia
• Myelodysplastic syndrome
• Thalassemia
• Chemotherapy
• Bone marrow and solid organ transplantation
• Oncologic disease
Mostly written to be associated with ALL
• Mimicking: Juvenile myelomonocytic leukaemia |
| Human bocavirus (HBoV) |
• Genotype 1 mostly seen in respiratory tract illness:
Pharyngitis
Sinusitis
Otitis media
Bronchitis
Astma
Pneumonia
• Genotype 2 mostly seen in gastro-intestinal illness
• Genotype 3 mostly seen in gastro-intestinal illness
• Genotype 4 mostly seen in gastro-intestinal illness |
| Parvovirus 4 (PARV) |
|
• Genotype 1-3:
Clinical presentation largely unknown, but
usually seen in gastro-intestinal and respiratory
illness |
| Bufavirus |
|
• Only described once in patients with acute diarrhoea
|
|
* References of the diseases in this table not mentioned. |