Blood Erythrocyte

Lipid peroxidation

Catalase

Superoxide dismutase

Glutathione reductase

GSH (glutathione)

Control 4.88(0.28) 89.73(2.84) 4.28(0.16) 14.24(0.84) 0.42(0.03)
30 days 4.89(0.11) 89.72(2.60) 4.2990.200 14.25(0.07) 0.41(0.92)
60 days 4.98(0.18)* 89.05(2.42)* 4.21(0.18)* 14.24(0.01)* 0.40(0.13)*
Liver cont 4.52(0.37) 89.12(2.03) 4.36(0.17) 14.19(1.37) 0.47(0.25)
30 days 4.52(0.20) 88.37(1.87) 4.31(0.15) 14.18(0.08) 0.46(0.14)
60 days 5.04(0.62)* 84.45(3.00)* 3.98(0.17)* 13.08(0.02)* 0.42(0.26)*
Kidney cont 3.96(0.52) 78.24(0.96) 4.08(0.08) 14.50(0.21) 3.09(0.01)
30 days 4.01(0.34) 77.81(2.65) 4.05(0.69) 14.34(0.22) 3.05(0.04)
60 days 5.24(0.65)* 76.88(0.12)* 3.98(0.23)* 13.24(0.57)* 3.08(0.02)
Lipid peroxidation: nmol malondialdehyde/ml packed erythrocytes; Catalase: nmol H2O2 utilized/min/mg hemoglobin; Superoxide dismutase: One unit is μg hemoglobin required to inhibit 3-(4-5 dimethyl thiazol 2-xl) 2, 5-diphenyl tetrazolium bromide reduction by 50%; Glutathione reductase: μmol NADPH utilized/min/g hemoglobin. ( ) Values represent mean ± SE (n = 3). *p<0.05 compared to control
Table 1: Lipid peroxidation and antioxidative systems in erythrocytes, liver and kidney of male rats exposed to insecticide Raid® for 30 days and /or 60 days.