| Histopathological changes |
Group |
Control group |
Lead Acetate Intoxicated Group |
Ajwa Extract Group |
Lead Acetate and Ajwa Extract Group |
| Group I |
Group II |
Group III |
Group IV |
| Liver |
|
|
|
|
| Hepatoportal and Sinusoidal congestion |
- |
+++ |
- |
+ |
| Cloudy swelling & Hydropic degeneration |
- |
+++ |
- |
+ |
| Cellular necrosis (Nuclear pyknosis, karyorrhexis, karyolysis) |
- |
++ |
- |
-/+ |
| Inflammatory cellular infiltrate |
- |
++ |
- |
- |
| Cholestasis |
- |
++ |
- |
+ |
| Kidneys |
|
|
|
|
| Vascular congestion |
- |
+++ |
- |
+ |
| Cloudy swelling |
- |
+++ |
- |
+ |
| Obliteration of bowman's capsule |
- |
++ |
- |
- |
| Interstitial and tubular hemorrhage |
- |
++ |
- |
- |
| Focal tubular necrosis |
- |
++ |
- |
- |
| Heart |
|
|
|
|
| Vascular congestion |
- |
++ |
- |
-/+ |
| Cardiac muscle, cloudy swelling and loss of striation |
- |
++ |
- |
+ |
| Cardiac muscle necrosis |
- |
++ |
- |
- |
| Lungs |
|
|
|
|
| Congestion of alveolar capillaries |
- |
+++ |
- |
+ |
| Edema &Thickening of alveolar wall |
- |
+++ |
- |
+ |
| Alveolar edema (pink coagulum in lumen) |
- |
+ |
- |
- |
| Alveolar Inflammatory cellular infiltrate |
- |
+++ |
- |
-/+ |
| Alveolar wall destruction |
- |
++ |
- |
- |
