Source Finished Distribution Compounds MRL max med max med max med Pharmaceuticals               Atenolol 0.25 36 2.3 18 1.2 0.84 0.47 Atorvastatin 0.25 1.4 0.80 <MRL <MRL <MRL <MRL Carbamazepine 0.50 51 4.1 18 6.0 10 6.8 Diazepam 0.25 0.47 0.43 0.33 0.33 <MRL <MRL Diclofenac 0.25 1.2 1.1 <MRL <MRL <MRL <MRL Fluoxetine 0.50 3.0 0.80 0.82 0.71 0.64 0.64 Gemfibrozil 0.25 24 2.2 2.1 0.48 1.2 0.43 o-hydroxy atorvastatin 0.50 1.2 0.70 <MRL <MRL <MRL <MRL p-hydroxy atorvastatin 0.50 2.0 1.0 <MRL <MRL <MRL <MRL Emprobamate 0.25 73 8.2 42 5.7 40 5.2 Naproxen 0.50 32 0.90 <MRL <MRL <MRL <MRL Norfluoxetine 0.50 <MRL <MRL <MRL <MRL 0.77 0.77 Phenytoin 1.0 29 5.1 19 6.2 16 3.6 Risperidone 2.5 <MRL <MRL <MRL <MRL 2.9 2.9 Sulfamethoxazole 0.25 110 12 3.0 0.39 0.32 0.32 Triclosan 1.0 6.4 3.0 1.2 1.2 <MRL <MRL Trimethoprim 0.25 11 0.80 <MRL <MRL <MRL <MRL Known and potential EDCs               Atrazine 0.25 870 32 870 49 930 50 17β-estradiol 0.50 17 17 <MRL <MRL <MRL <MRL Estrone 0.20 0.90 0.30 <MRL <MRL <MRL <MRL 17α-ethynylestradiol 1.0 1.4 1.4 <MRL <MRL <MRL <MRL Bisphenol A 5.0 14 6.1 25 25 <MRL <MRL Butylbenzyl phthalate 50 54 53 <MRL <MRL <MRL <MRL Diethylhexyl phthalate 120 170 150 <MRL <MRL <MRL <MRL Galaxolide 25 48 3 33 31 <MRL <MRL Linuron 0.50 9.3 4.1 6.2 6.1 <MRL <MRL Nonylphenol 80 130 100 100 93 110 97 Progesterone 0.50 3.1 2.2 0.57 0.57 <MRL <MRL Testosterone 0.50 1.2 1.1 <MRL <MRL <MRL <MRL

Table1: Method reporting limits (MRLs), maximum concentration (max), median concentration (med) of pharmaceuticals and EDCs in source water, finished water, and distribution systems. All concentrations are presented in ng/L. (The data were from Benotti et al. [17]).