Event/signaling Cav-1 KO  Cav-2  KO
Survival

NC

Lung permeability (Evans Blue)

NC

Small intestinal (Colon and Ileum) permeability (Evans Blue)

NC

Small intestinal (Ileum) tissue damage

NC?

iNOS expression (Colon lysates)

NO production (Peritoneal lavage)

STAT-1 Y701 phosphorylation (Colon lysates)

Table 4: Antagonistic effect of Cav-1 and Cav-2 on the events and signaling associated with LPS-induced sepsis in mice. Relative increase (↑), decrease (↓), or no change (NC) in Cav-1 and Cav-2 KO compared to WT mice are shown based on the results of study by de Almeida et al. [11].