Patients: |
1 |
2 |
3 |
4 |
5 |
6 |
7 |
9 |
10 |
11 |
12 |
Abnormal results |
PT (RNI;1.0-1.2) |
1.0 |
ND |
1.0 |
1.0 |
ND |
1.0 |
1.0 |
1.1 |
ND |
90%
(70-120) |
ND |
0/8 |
aPTT (Pt/Cnt; <1.3) |
1.53 |
ND |
1.1 |
1.2 |
ND |
1.0 |
1.1 |
0.9 |
ND |
1.0 |
ND |
1/8 |
Factor VIII (60-150%) |
>200 |
>200 |
126 |
92 |
>200 |
>200 |
>200 |
168 |
33 |
108 |
67 |
7/11 |
Factor XI (60-140%) |
20 |
58 |
79 |
83 |
43 |
29 |
53 |
78 |
110 |
94 |
53 |
6/11 |
Antithrombin (80-120%) |
37 |
79 |
74 |
91 |
30 |
ND |
76 |
100 |
102 |
60 |
109 |
4/10 |
Protein C (70-130%) |
34 |
100 |
112 |
131 |
32 † |
86 |
71 |
104 |
97 |
80 |
90 |
4/11 |
Protein S (70-130%) |
49 |
70 |
65 |
70 |
51╪ |
62 |
65 |
74 |
55 ‡ |
60 ‡ |
79╪ |
7/11 |
|
| Normal values in parenthesis; Abnormal values are in bold.
Patients 8 and 13 had no coagulation tests performed. All patients had normal results for factor IX.
aPTT: activated partial tromboplastin time; PT: protrombin time; Pt: patient; Cnt: control; ND:not done; reference ranges †: 70-120%; ‡ : 64-126%; + : 72-150%. |
| Table 3: Plasma levels of prothrombin time, activated partial thromboplastin time, coagulation factors, and anticlotting factors of PMM2-CDG patients. |