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Figure 9: Effects of chronic ethanol feeding and PPAR agonist treatments on inflammatory cytokine and oxidative stress indices in liver. (A) IL-1β, (B) IL6, (C) TNF-α, (D) 4- hydroxynonenal (HNE), (E) 3-nitrotyrosine (NTyr), and (F) β-actin were measured in liver homogenates by (A-C) multiplex or (D-F) duplex ELISAs. Inter-group comparisons were made using two-way ANOVAs with Bonferroni posttests (N=12 samples/group). P-values corresponding to significant within-treatment group differences (P<0.05 or better) are indicated. |