| |
Overall (N=487) |
Full Sections (n=147) |
0.6 mm cores
(n=126) |
1 mm cores
(n=214) |
P-value |
| Age (Mean (SD)) |
56.1 (11.8) |
55.0 (11.3) |
55.7 (13.0) |
57.0 (11.5) |
0.286 |
| Time to diagnosis in days - Median (range) |
153 (0, 1729) |
118 (43, 884) |
663.5 (0, 1729) |
97 (3, 830) |
<0.001 |
| Histology |
|
|
|
|
|
| Borderline, n (%) |
73 (15.0) |
34 (23.1) |
18 (14.3) |
21 (9.8) |
|
| Invasive, n (%) |
414 (85.0) |
113 (76.9) |
108 (85.7) |
193 (90.2) |
|
| Serous, n (%) |
256 (61.8) |
78 (69) |
59 (54.6) |
119 (61.7) |
0.031 |
| Non-Serous, n (%) |
110 (26.6) |
23 (20.4) |
39 (36.1) |
48 (24.9) |
| Clear cell |
23 (5.5) |
6 (5.3) |
5 (4.6) |
12 (6.2) |
0.264 |
| Endometriod |
61 (14.7) |
9 (7.9) |
26 (24.1) |
26 (13.5) |
| Mucinous |
26 (6.3) |
8 (7.1) |
8 (7.4) |
10 (5.2) |
| Other* |
48 (11.6) |
12 (10.6) |
10 (9.3) |
26 (13.4) |
|
| Family History (based on 1st and 2nd degree relatives) |
| # (%) of subjects with relatives with CRC |
86 (17.6) |
22 (15) |
25 (19.8) |
39 (18.2) |
0.565 |
| # (%) of subjects with relatives with EC |
28 (5.7) |
9 (6.1) |
4 (3.2) |
15 (7) |
0.335 |
| # (%) of subjects with relatives with any HNPCC cancers** |
168 (34.5) |
52 (35.4) |
39 (31) |
77 (36) |
0.632 |
*Other includes the following histologies: Carcinoma, unspecified (26), Mixed cell (13), Peritoneal (3), and Transitional cell carcinoma (6); **HNPCC cancers included:
colorectum, endometrium, other gastrointestinal tract, urinary tract, ovary and brain; Abbreviations: CRC: colorectal cancer; EC: endometrial cancer. |
