Groups
Degeneration
CA1
CA3
CA4
DG
p (Comparing to control G1)
Group 2
Grade 0
10.58 ± 0.03
10.86 ± 0.09
11.97 ± 0.09
14.64 ± 0.05
Grade 1
1.92 ± 0.06
4.43 ± 0.07
4.32 ± 0.80
3.83 ± 0.03
p<0.05
Grade 2
1.56 ± 0.02
2.75 ± 0.01
4.58 ± 0.62
4.91 ± 0.91
Group 3
Grade 0
10.52 ± 0.01
10.65 ± 0.01
11.82 ± 0.01
14.57 ± 0.01
Grade 1
1.77 ± 0.01
4.27 ± 0.01
4.43 ± 0.01
3.82 ± 0.03
p<0.05
Grade 2
1.51 ± 0.01
2.74 ± 0.01
6.08 ± 0.02
7.03 ± 0.02
Group 4
Grade 0
10.59 ± 0.05
10.65 ± 0.01
12.00 ± 0.12
14.63 ± 0.02
Grade 1
1.81 ± 0.03
4.33 ± 0.04
4.37 ± 0.02
3.80 ± 0.04
p<0.05
Grade 2
1.53 ± 0.01
2.79 ± 0.02
5.35 ± 0.51
5.92 ± 0.74
Group 5
Grade 0
10.69 ± 0.24
10.40 ± 0.15
12.07 ± 0.18
14.79 ± 0.16
Grade 1
1.85 ± 0.06
4.35 ± 0.04
4.24 ± 0.09
3.77 ± 0.09
p<0.05
Grade 2
1.49 ± 0.01
2.95 ± 0.17
4.83 ± 0.60
5.43 ± 0.77
Group 6
Grade 0
10.57 ± 0.02
10.64 ± 0.10
12.61 ± 0.29
14.39 ± 0.07
Grade 1
2.01 ± 0.08
4.40 ± 0.19
4.83 ± 0.19
3.86 ± 0.06
p<0.05
Grade 2
1.68 ± 0.07
2.67 ± 0.02
4.90 ± 0.43
4.59 ± 0.85
Group 7
Grade 0
10.40 ± 0.07
11.48 ± 0.49
12.04 ± 0.14
14.29 ± 0.13
Grade 1
1.85 ± 0.03
4.30 ± 0.02
4.28 ± 0.07
3.89 ± 0.04
p<0.05
Grade 2
1.63 ± 0.06
2.39 ± 0.20
5.22 ± 0.36
6.78 ± 0.17
All groups
p (Between sides)
Right hemisphere
Grade 0
10.47 ± 0.11
10.87 ± 0.08
9.93 ± 0.42
14.82 ± 0.17
p>0.05
Grade 1
1.40 ± 0.04
1.26 ± 0.09
1.29 ± 0.06
1.44 ± 0.09
Grade 2
1.06 ± 0.06
1.24 ± 0.12
1.24 ± 0.04
1.10 ± 0.10
Left hemisphere
Grade 0
10.47 ± 0.10
10.86 ± 0.08
10.10 ± 0.40
15.52 ± 0.27
Grade 1
1.34 ± 0.03
1.10 ± 0.06
1.26 ± 0.06
1.40 ± 0.06
Grade 2
1.04 ± 0.06
1.60 ± 0.06
1.13 ± 0.02
1.12 ± 0.01
Table 2:
Histopathologic evaluation; means and SEMs of the neuron numbers in unit area (Grade 0, normal appearance; Grade 1, moderately degenerated; Grade 2, highly degenerated neurons with pyknotic nuclei and dark appearances).
