Figure 1: H&E stained sections of left ventricular myocardium of all studied groups. (1A): Showing normal long parallel longitudinal cardiomyocytes (m) with acidophilic cytoplasm, oval central nuclei (n), narrow interstitial spaces with few interstitial nuclei (arrows) in control subgroup. Higher magnification in boxed area is showing vesicular myonucleus and interstitial nuclei. (1B): normal myocardial arteriole of control subgroup with thin intima, tunica media (md) and adventitia (a). Cut sections of cardiomyocytes (m) with centrally located nuclei (n) are seen. (1C, D): showing sections in 30 days treated group with irregular cardiac fibers (f) with faint cytoplasm, prominent nuclei (n) in longitudinal section (1C) and deeply eosinophilic myocyte (em) surrounded with paler myocyte (pm) in transverse section (1D). (Scale bar=50μm, boxed areas X 3 times). (1E, F, H): Showing transverse section of cardiomyocyte of 60 days dioxins treated group with many connective tissue nuclei (arrows), ground substance (*), peripheral myonuclei (arrow heads) in (1E and higher magnification in boxed area). Vacuolated myocytes (V) with apoptotic nuclei (arrow head) is seen in (1F). Extravasated RBCs (r) inbetween large transverse fibers (f) are seen in (1H). (1G): showing longitudinal section of cardiomyocyte of 60 days dioxins treated group with irregular widely separated longitudinal fibers (f), apoptotic nuclei (arrow heads) and prominent interstitial cells nuclei (arrows). (Scale bar=50 μm, boxed area×3 time). Figure (1I, J): showing H and E stained sections of 60 days dioxins treated group. (1I): showing lightly eosinophilic areas that contained numerous connective tissues (*). (1J): haphazard disorganization of medial nuclei of myocardial arteriole. The media (md) and adventitia (a) are surrounded with prominent connective tissue (c). (1K, L): showing congestion of blood capillaries (bc), interstitial muclei (arrows) and apparent normal myocardial arteriole in dioxins+vitamins supplemented group (scale bar=50 μm, boxed area×3times).