|   | 
        Incidence | 
        Relative    risk | 
        Hazard    ratio | 
          | 
       
      
        | Bleeding  | 
        2.2-3.0% | 
        1.91-2.48 | 
          | 
        [17-19, 28]  | 
       
      
        | Arterial    thromboembolic events  | 
        1.0-2.3% | 
          | 
        1.82-2.0 | 
        [17-19, 22,26,27]  | 
       
      
        | Proteinuria   | 
        1.0% | 
          | 
          | 
        [19]  | 
       
      
        | Gastrointestinal    perforation  | 
            0.9-2.0% | 
          | 
          | 
        [17-19] | 
       
      
        | Wound    healing complications  | 
        1.0-3.5% | 
          | 
          | 
        [17-19, 29]  | 
       
      
        | Hypertension  | 
        5.3-23.6% | 
        2.98-5.28 | 
          | 
        [17-19, 23, 25]  | 
       
      |