| |
Univariate analysis (log-rank test) |
Multivariate analysis (Cox proportional hazards model) |
| Variables |
Statistic |
df |
P |
Hazard ratio |
95%CI |
P |
| Sex |
2.37 |
1 |
0.1236 |
|
|
|
| Age |
0.56 |
1 |
0.4534 |
|
|
|
| Macro type |
2.05 |
3 |
0.5627 |
|
|
|
| Site |
3.24 |
2 |
0.1977 |
|
|
|
| The number of site |
0.51 |
2 |
0.7743 |
|
|
|
| P |
15.87 |
1 |
0.0001* |
0.826 |
0.192-3.556 |
0.797 |
| Depth |
3.57 |
2 |
0.1676 |
|
|
|
| Histology |
5.14 |
1 |
0.0234* |
2.873 |
1.342-6.151 |
0.007* |
| Stroma |
2.74 |
2 |
0.2542 |
|
|
|
| INF |
0.39 |
2 |
0.8209 |
|
|
|
| ly |
5.12 |
2 |
0.0773 |
|
|
|
| v |
0.11 |
1 |
0.7444 |
|
|
|
| LN metastasis |
9.50 |
2 |
0.0086* |
1.340 |
0.728-2.465 |
0.347 |
| M1 |
0.00 |
1 |
0.9725 |
|
|
|
| Gastrectomy |
6.56 |
1 |
0.0104* |
- |
- |
- |
| St. IV factor |
9.09 |
1 |
0.0026* |
2.412 |
0.831-7.004 |
0.105 |
| New drugs |
0.27 |
1 |
0.6011 |
|
|
|
| LN dissection |
1.08 |
1 |
0.2991 |
|
|
|
| Tumor size |
0.03 |
1 |
0.8578 |
|
|
|
| R |
0.12 |
1 |
0.7309 |
|
|
|
| M1(LYM) |
0.99 |
1 |
0.3196 |
|
|
|
| Liver meta (1) |
0.12 |
1 |
0.7280 |
|
|
|
| Liver meta (2) |
4.36 |
1 |
0.0368* |
1.520 |
0.707-3.267 |
0.284 |
| Hepatectomy |
3.25 |
1 |
0.0716 |
|
|
|
| HAI |
10.46 |
1 |
0.0012* |
0.226 |
0.104-0.494 |
< 0.001* |
| Systemic chem. |
30.79 |
1 |
< 0.0001* |
0.233 |
0.099-0.546 |
0.001* |
df degree of freedom, CI confidential interval, P peritoneal metastasis, INF tumor infiltrative pattern, ly lymphatic invasion, v venous invasion, M1 distant organ metastasis,
LN lymph node, R residual tumor, M1(LYM) distant lymph node metastasis, Liver meta (1) the number of metastatic nodule (solitary or multiple), Liver meta (2) the number
of metastatic nodule (≤ 3 or 4 ≤), HAI hepatic arterial infusion, chem. Chemotherapy *P<0.05 indicates statistical significance |
