Variable

Yes

No

P

Total

Median TTP

Total

Median TTP

N

(%)

Hours

(range)

N

(%)

Hours

(range)

Characteristics

 

 

 

 

 

 

 

 

 

    Age > 60 years

117

(71.3)

13.3

(3.6-95.2)

50

(29.9)

14.5

(7.3-65.1)

0.256

    Male

100

(59.9)

14.1

(3.6-95.2)

67

(40.1)

12.6

(4.4-69.9)

0.074

    Charlson score ≥5

123

(73.7)

13.6

(3.6-95.2)

44

(26.3)

13.2

(7.9-52.6)

0.740

    MRSA

55

(32.9)

13.5

(7.9-81.5)

112

(67.1)

13.5

(3.6-95.2)

0.934

    Community-acquired

72

(43.1)

12.4

(7.2-69.9)

95

(56.9)

12.4

(7.2-69.9)

0.032

    Attributable mortality

46

(27.5)

13.2

(3.6-82.0)

117

(70.1)

13.6

(4.4-95.2)

0.558

Comorbidities

 

 

 

 

 

 

 

 

 

    Cardiac insufficiency

92

(55.1)

13.2

(3.6-74.8)

75

(44.9)

14.4

(7.2-95.2)

0.053

    Peripheral arterial disease

18

(10.8)

13.2

(4.4-28.0)

149

(89.2)

13.6

(3.6-95.2)

0.541

    Diabetes

50

(29.9)

12.4

(7.9-65.2)

117

(70.1)

13.8

(3.6-95.2)

0.156

   COPD

50

(29.9)

14.1

(3.6-95.2)

117

(70.1)

12.8

(4.4-81.5)

0.040

    Prothesis

43

(25.7)

15.4

(3.6-81.9)

124

(74.3)

13.2

(7.0-95.2)

0.222

    Stroke

67

(40.1)

15.4

(8.2-81.9)

100

(59.9)

12.9

(3.6-95.2)

0.016

    Drug user

8

(4.9)

21.7

(10.2-38.4)

159

(95.2)

13.3

(3.6-95.2)

0.018

Criteria of severity

 

 

 

 

 

 

 

 

 

    Complicated bacteremia

32

(19.2)

12.4

(7.2-38.4)

135

(80.8)

13.8

(3.6-95.2)

0.088

    Persistent bacteremia

15

(9.0)

11.6

(4.4-18.5)

152

(91.0)

13.8

(3.6-95.2)

0.010

    Intensive care unit stay

51

(30.5)

13.0

(3.6-52.6)

116

(69.5)

13.6

(7.0-95.2)

0.074

    Prolonged hospitalization

103

(61.7)

14.0

(3.6-95.2)

64

(38.3)

12.7

(7.2-69.9)

0.478

Source of bacteremia

 

 

 

 

 

 

 

 

 

    Primary (a)

22

(13.2)

13.0

(4.4-23.2)

145

(86.8)

13.7

(4.4-23.2)

0.435

    Primary related to catheter (b)

36

(21.6)

11.6

(3.6-95.2)

131

(78.4)

13.9

(4.4-81.9)

0.019

    Secondary endovascular (c)

25

(15.0)

12.4

(7.2-32.7)

142

(85.0)

13.8

(3.6-95.2)

0.037

        Endocarditis

18

(10.8)

11.0

(7.2-32.7)

149

(89.2)

13.8

(3.6-95.2)

0.006

    Central (a+b+c)

83

(49.7)

12.2

(3.6-95.2)

84

(50.3)

15.5

(7.0-81.9)

<0.001

Table 3: Univariate analysis of different variables and TTP among 167 episodes of S. aureus bacteremia.