UU UC UA UG CU CC CA CG Axis 1 r 0.660 0.680 -0.779 0.774 0.311 -0.711 -0.035 -0.370   P <0.001 <0.001 <0.001 <0.001 0.105 <0.001 0.849 0.053     AU AC AA AG GU GC GA GG Axis 1 r 0.579 -0.621 0.683 -0.715 -0.396 0.730 -0.157 -0.260   P <0.01 0.001 <0.001 <0.001 0.038 <0.001 0.406 0.173

Table 2: Summary of correlation analysis between the first axis in COA and sixteen dinucleotides frequencies in complete CVB codes.