Figure 3: Photomicrographs of cross sections in the liver of the cisplatinum treated group showing: (a): Congestion of the central vein (C) and sinusoids (S). Note the presence of massive intracytoplasmic vacuolations (V) and kupffer’s cells (arrows). (H & E x400) (b) Massive intracytoplasmic vacuolation (V), karryorehxis (kr) and margination of chromatin inside the nucleus (arrow). Note kupffer’s cells (kc) and sinusoidal congestion (C). (H & E x 1000) (c) Karryorehxis (kr), pyknotic nuclei (p) and hemosiderin granules (arrow). (H & E x 1000) (d) Intranuclear vacuolations (black v) and intracytoplasmic vacuolations (red v). Note the margination of the chromatin inside the nucleus (arrow). (Toludine blue x 1000)