Study ID
(author,
year)

N

Design

Setting

Participants

Participants Intervention
(experimental
group)

Intervention
(control group)
Study

Follow up

Weibull et al.
(1993)

58

Randomized
controlled
clinical trial

Hospital,
Sweden

58 patients without diabetes with severe
hypertension and
significant stenosis

Percutanesous
Transluminal Renal
Angioplasty (PTRA)

Operation

24 mo

Webster etal.
SNRASCG-trial
1998

135

Randomized
controlled
clinical trial

Scottish Hospitals
Endowments Research Trust.

135 eligible patients with hypertension and  renovascular disease were identified

Percutanesous
transluminal renal
angioplasty (PTRA

Anti-hypertensive drug
therapy

3–54 months

Plouin et al
EMMA
(1998)

49

Randomized
controlled
clinical trial

Hospital Broussais, and INSERM U-36 (P.-F.P.), Paris, France.

Patients were randomly assigned antihypertensive  drug treatment (control group,
n.(26) or angioplasty n. (23)

Percutanesous
transluminal renal
angioplasty (PTRA) with or without stent

Anti-hypertensive drug
therapy

6 month

van deVen
et al.
(1999)

85

Randomized
controlled
clinical trial

Utrecht
University
hospital,
Netherlands

85 patients with
Ostial atherosclerotic
renal artery stenosis

Percutaneous
Transluminal
Angioplasty (PTA)

Angioplasty with stent placement (PTAS)

6 mo

Jaarsveld
et al.
DRASTIC
(2000)

106

Randomized
controlled
clinical trial

Multicentre, US

106 patients with
hypertension who
had atherosclerotic
renal-artery stenosis

Percutaneous
transluminal renal
angioplasty

Anti-hypertensive drug therapy

12 mo

Uzzo et al(2002)

52

Randomized controlled clinical trail

Cleveland
Clinic Foundation

52 patients with atherosclerotic renovascular disease and hypertension

surgical

medical

74 month

Wheatley et al
ASTRAL trial
(2007)

806

Randomized
controlled
clinical trial

57 hospitals (53 in the United
Kingdom, 3 in Australia, and 1 in New Zealand).

806 patients with atherosclerotic
renovascular disease either to undergo revascularization in addition to receiving
medical therapy or to receive medical therapy alone

(angioplasty either alone or with stenting with or without medical management

Medical management (statins, antiplatelet agents, and
optimal blood-pressure control)

34 months

Bax et al
STAR trail
(2009)

140

Randomized
controlled
clinical trial

10 European medical centers.

Stent placement and medical treatment (64 patients) or medical treatment only (76 patients).

stent placement and medical treatment

Medical treatment consisted
of antihypertensive treatment, a statin, and aspirin

24 month

Balzer et al
RAOOD
(2009)

49

Randomised
controlled
clinical trial

University of Düsseldorf

49 patient with ARVD underwent either Open surgical reconstructive procedure or PTRA± stenting

 

surgery

Renal artery angioplasty± stenting

72 month

Table 2: Characteristics of included studies.