Figure 1: Development of salt-induced hypertension in Dahl rats. DS8%: Dahl salt-sensitive rats fed an 8% NaCl diet (high-salt diet); DS0.4%: Dahl salt-sensitive rats fed a 0.4% NaCl diet (regular diet); DR8%: Dahl saltresistant rats fed an 8% NaCl diet; DR0.4%: Dahl salt-resistant rats fed a 0.4% NaCl diet; SAP: systolic arterial pressure measured with the tail cuff method in conscious rats; Age: rat age. *: p < 0.005 vs. DS0.4%; †: p < 0.05 vs. the initial (8-week) value for DS8%. The high-salt diet produced marked hypertension in Dahl salt-sensitive rats [28].