Figure 7: Putative characteristics of the blood pressure control system and the target organs in Dahl salt-sensitive hypertension [53]. Baro: Arterial Baroreceptors; CNS: Central Nervous System; Nr Inside An Airplane: Neural Outputs From The CNS; H Inside A Ship: Humoral Outputs From The CNS; Ht: Heart; TPR: Total Peripheral Resistance; VOL: Circulating Blood Volume; AP: Arterial Pressure; PSN: Peripheral Sympathetic Nerves [53]. In Dahl hypertensive rats, the sympathetic center becomes pathophysiologically hyper-reactive, concomitant with compensatory upregulated activity in nNOS neuron-mediated inhibitory systems of the central sympathetic center, which is a dilemma in the sympathetic center, resulting in almost same activity in resting peripheral sympathetic nerve in hypertensive Dahl rats as that in normotensive Dahl rats. Once the NO-mediated inhibitory system is suppressed due to some stimuli, hypertensive Dahl rats produce hyperreactivity in peripheral sympathetic activity. On the other side of the target organs, the kidney functions abnormally, and the peripheral vascular system shows hypertrophy and abnormally functioning endothelium.