Variables groups Mean of differences P- value
Raloxifene/ experimental N=18 Placebo/control N=19
BMI (Kg/m2) 30.6 ± 4.1 29.4 ± 4.3 1.21 0.423
SBP(mmHg) 135 ± 19.9 134.4 ± 17.9 1.5 0.81
DBP(mmHg) 81 ± 7.5 85.3 ± 10.2 -3.4 0.35
HbA1C(mg/dL) 7.9 ± 2.1 7.7 ± 1.7 -0.14 0.83
TG(mg/dL) 240.4 ± 98.6 165.1 ± 78.2 75.3 0.0231
Chol(mg/dL) 200.6 ± 47.2 186.4 ± 41.7 14.2 0.372
HDL(mg/dL) 40.9 ± 5.1 43.7 ± 6.4 2.8 0.18
LDL(mg/dL) 112.2 ± 44.1 108.8 ± 38.1 3.4 0.81
ACR log 1.89 ± 0.8 2.12 ± 0.83 -0.23 .043
GFR(ml/min) 66.3 ± 17.1 69 ± 22.9 2.7 0.70
1-P value< 0.05 is considered statistically significant
BMI: Body Mass Index; SBP: Systolic Blood Pressure; DBP: Diastolic Blood Pressure; TG: Triglyceride; Chol: Cholesterol; HDL: High Density Lipoprotein; LDL: Low Density Lipoprotein; ACR: Albumin to Creatinin ratio; ACR log: Logarithm of ACR; GFR: Glomerular Filtration Rate
Table 5: Comparison of the mean values of clinical and biochemical parameters in postmenopausal women taking raloxifene with those taking placebo at end of the study.