|
eNOS-/- db/db |
eNOS-/- high-dose STZ |
eNOS-/- low-dose STZ |
eNOS-/- low-dose STZ, HF |
eNOS-/- Akita |
eNOS+/- Akita |
|
Ref.16 |
Ref.15 |
Ref.40 |
Ref.14 |
Ref.47 |
Ref.47 |
u-albumin |
|
|
|
|
|
|
GFR |
¯ |
not determined |
¯ |
¯ |
¯ |
|
GBM thickening |
+ |
+ |
+ |
+ |
+ |
+ |
mesangial expansion |
+ |
+ |
+ |
+ |
+ |
+ |
mesangiolysis |
+ |
+ |
+ |
- |
+ |
+ |
nodular sclerosis |
+ |
+ |
+ |
+ |
+ |
+ |
tubulointerstitial fibrosis |
- |
+ |
- |
+ |
- |
- |
arteriolar hyalinosis |
+ |
+ |
not determined |
- |
- |
- |
|