Deceased Donor Transplants

Living Donor Transplants

FCXM result

aHR

95% CI

P-value

aHR

95% CI

P-value

T–B–

reference

Reference

T–B+

1.16

1.05–1.28

0.003

1.32

1.13–1.55

0.0004

T+, B not measured

1.44

1.12–1.87

0.005

1.40

1.02–1.93

0.04

T+B+

1.21

1.03–1.43

0.02

1.65

1.34–2.04

<0.0001

aHR, adjusted hazard ratio.
Regression models were adjusted for the following factors as covariates: recipient age category (<18, 19-30, 31-45, 46-60, or >61), gender, race (black, white, or other), Hispanic ethnicity, cause of end-stage renal disease (diabetes, hypertension, glomerulohephritis, other), duration of pre-transplant dialysis, peak panel reactive antibodies (<10%, 11%-30%, or >30%), retransplant status, and comorbidities (diabetes, hypertension, peripheral vascular disease, chronic obstructive pulmonary disease); category, gender, race, hypertension, diabetes, and subtype for deceased donors (expanded criteria, donation after cardiac death); degree of HLA mismatch (0 ABDR, 0 DR, or DRmismatch), cold ischemia time. All models were stratified by transplant year.
*Adapted from Table 4 in [22] with permission of the publisher.

Table 2: Significant associations of flow cytometry crossmatch results with the relative risk of five-year allograft loss by multivariable Cox regression, adjusted for clinical covariates at transplant (1995 –2007).*