Deceased Donor Transplants |
Living Donor Transplants |
FCXM result |
aHR |
95% CI |
P-value |
aHR |
95% CI |
P-value |
T–B– |
reference |
Reference |
T–B+ |
1.16 |
1.05–1.28 |
0.003 |
1.32 |
1.13–1.55 |
0.0004 |
T+, B not measured |
1.44 |
1.12–1.87 |
0.005 |
1.40 |
1.02–1.93 |
0.04 |
T+B+ |
1.21 |
1.03–1.43 |
0.02 |
1.65 |
1.34–2.04 |
<0.0001 |
aHR, adjusted hazard ratio.
Regression models were adjusted for the following factors as covariates: recipient age category (<18, 19-30, 31-45, 46-60, or >61), gender, race (black, white, or other),
Hispanic ethnicity, cause of end-stage renal disease (diabetes, hypertension, glomerulohephritis, other), duration of pre-transplant dialysis, peak panel reactive antibodies
(<10%, 11%-30%, or >30%), retransplant status, and comorbidities (diabetes, hypertension, peripheral vascular disease, chronic obstructive pulmonary disease); category,
gender, race, hypertension, diabetes, and subtype for deceased donors (expanded criteria, donation after cardiac death); degree of HLA mismatch (0 ABDR, 0 DR, or DRmismatch),
cold ischemia time. All models were stratified by transplant year.
*Adapted from Table 4 in [22] with permission of the publisher. |