Figure 1


Figure 1: Urine protein: creatinine values for Fisher to Lewis rats undergoing heterotopic renal transplantation, bilateral native nephrectomy, and receiving water (triangle, 0.25 mL oral, once daily) or spironolactone (diamond, 10 mg/kg, oral, once daily). Control rats underwent uninephrectomy and received water (cricles) or spironolactone (squares) at the same doses and frequencies. * = significant increase in UP:UC in both transplant groups (p = 0.03 spironolactone and 0.04 water) compared to week 0. No difference was detected between groups at any time point.

Figure 1: Urine protein: creatinine values for Fisher to Lewis rats undergoing heterotopic renal transplantation, bilateral native nephrectomy, and receiving water (triangle, 0.25 mL oral, once daily) or spironolactone (diamond, 10 mg/kg, oral, once daily). Control rats underwent uninephrectomy and received water (cricles) or spironolactone (squares) at the same doses and frequencies. * = significant increase in UP:UC in both transplant groups (p = 0.03 spironolactone and 0.04 water) compared to week 0. No difference was detected between groups at any time point.