Table 1

Week post nephrectomy	Water and nephrectomy control	Spironolactone and nephrectomy control	Spironolactone and transplantation	Water and transplantation
0	0.50 ± 0.00	0.50 ± 0.00	0.52 ± 0.02	0.53 ± 0.02
0.14	0.80 ± 0.00^a,b,*	0.80 ± 0.03^c,d	1.36 ± 0.18^a,c,*	1.24 ± 0.08^b,d,*
0.42	0.80 ± 0.07^*	0.70 ± 0.04^e	1.06 ± 0.12^e,*,#	0.96 ± 0.04^*,#
1	0.60 ± 0.04^f	0.60 ± 0.00^g	0.88 ± 0.08^f,g,*,#	0.79 ± 0.05^*,#
2	0.60 ± 0.00	0.58 ± 0.03	0.80 ± 0.08^*,#,$,%	0.84 ± 0.06^*,#
3	0.58 ± 0.03	0.58 ± 0.03	0.80 ± 0.63^*,#,$,%	0.71 ± 0.04^#,$
4	0.63 ± 0.03	0.63 ± 0.03^h	0.86 ± 0.08^{h,*, #}	0.79 ± 0.01^*,#
6	0.65 ± 0.03	0.60 ± 0.00	0.80 ± 0.08^*,#,$,%	0.76 ± 0.02^*#
8	0.63 ± 0.03	0.68 ± 0.03	0.82 ± 0.04^*,#	0.81 ± 0.03^*,#
10	0.63 ± 0.03	0.68 ± 0.03	0.76 ± 0.07^#,$,%	0.70 ± 0.02^#,$
12	0.63 ± 0.03	0.65 ± 0.03	0.92 ± 0.09^*,#	0.77 ± 0.03^*,#
14	0.58 ± 0.03	0.60 ± 0.00	0.76 ± 0.09^#,$	0.69 ± 0.01^#,$
16	0.68 ± 0.03	0.65 ± 0.03	0.90 ± 0.13^*,#,%	0.81 ± 0.03^*,#

Table 1: Mean ± SEM serum creatinine concentrations (mg/dL) of rats on weeks following nephrectomy only (controls) or heterotopic renal transplantation and bilateral nephrectomy. Rats either received water (0.25 mL, oral, daily) or spironolactone (10 mg/kg, oral, daily). Values sharing a letter are statistically different (comparisons between groups). * = statistically different from baseline within a group, # = statistically different than week 0.14 with a group, $ = statistically different than week 0.42 within a group, % = statistically different than week 1 within a group.