Name of the Clan Name of the Gene family Phase 0 Phase 1 Phase 2 Total number of introns Total number of genes Gene family wise intron density* Unique introns Conserved introns**
CYP4 Clan CYP325 23 22 11 56 16 3.5 -- 7
CYP4 21 56 24 101 28 3.6 5 10
CYP3 Clan CYP6 10 29 6 45 30 1.5 5 8
CYP9 0 1 6 7 7 1 1 1
CYP329 0 0 1 1 1   -- --
CYP2 Clan CYP15 1 1 0 2 1   -- --
CYP303 1 0 1 2 1   -- --
CYP304 0 3 2 5 2 2.5 1 2
CYP305 0 3 3 6 3 2 2 0
CYP306 2 1 1 4 1   -- --
CYP307 0 3 1 4 2 2 2 2
Mitochondrial Clan CYP12 12 4 12 28 4 7 4 --
CYP49 4 2 4 10 1   -- --
CYP301 3 0 3 6 1   -- --
CYP302 1 3 2 6 1   -- --
CYP314 3 1 2 6 1   -- --
CYP315 3 2 2 7 1   -- --
    84 131 81 296 101      
Note: *intron density per gene family was calculated by dividing the total number of introns to the total number of genes. The gene families with only one gene are not
considered for the intron density analysis
**conserved intron designation was given when an intron found to be conserved in more than one gene of a respective gene family. And thus, the conserved and unique
introns were mentioned for only the gene families which have more than one gene. Some of the introns are found to be conserved in more than one gene family. Such
intronic positions are highlighted using vertical lines in the supplementary figure 2c
Table 1: Table showing intron phase, intron number and family-wise intron density distribution across different gene families of P450 superfamily of Anopheles gambiae