Purification step Volume (ml) Protein concentration (mg/ml) Total protein (mg) Activity (nmol min-1 ml-1) Total activity (nmol min-1 ) Specific activity (nmol min-1 mg-1 ) Purification factora Overall yield (%)b
Crude extract 152 2.06 ± 0.13 313.79 ± 1.33 1.494 ± 0.03 227.15 ± 4.67 0.74 ± 0.01 1 100
TCA ppt. extract 8 2.66 ± 0.56 21.29 ± 0.46 1.74 ± 0.07 13.92 ± 0.56 0.654 ± 0.03 0.88 6.13
20-80% ammonium sulfate ppt. extract 9 2.1 ± 1.24 17.494 ± 1.63 1.707 ± 0.01 15.36 ± 0.14 0.883 ± 0.07 1.19 6.76
Note: aDefined as: purification factor=(specific activity of fraction/specific activity of homogenate).
bDefined as: overall yield=total activity of fraction/total activity of homogenate)×100.
Table 1: Summary of protease purification of leaf.