Figure 2: Particle trajectory method. A: Confocal image of single cell stained with DNA intercalater PicoGreen. A large nucleus in almost center area within a cell and bright points in the cytoplasm can be observed. B: The area marked by a dotted square in A is enlarged for recording a time image series. C: Particles of mtDNA was extracted from each frame in the time image series through the setting proper threshold. Five particles used in this study are numbered from 1 to 5. D: Trajectories of center points of particles obtained by fitting ellipses. Analyzed particles are the same as C. E: Relationship between mean squared displacement and time. Particle #1 in C denotes closed triangle and the linear regression shows thin solid line, #2: open circle and thick solid line, #3: open square and chain line, #4: closed circle and solid line, #5: closed diamond and dotted line.