Figure 1: (A, B) The levels of serum Aβ40, Aβ42 and Aβ43 were measured using ELISA kits. All samples were measured in duplicate. A, ■ Aβ40, □ Aβ42; B, ■ Aβ43, □ Aβ43/ Aβ42. Aβ42 decreased in the serum of patients with AD compared with control subjects (p<0.001), whereas Aβ43 did not change or slightly increased, which resulted in a higher Aβ43/42 ratio in patients with AD (p=0.08). Data represent mean ± SEM; p was determined by the Mann- Whitney U-test. Control subjects, n=18; AD, n=26.