| P53 R282W p53 gene mutation |
| Variables |
+ve case |
- ve case |
Chi-Square |
df |
P value |
| Males |
50(62.5%) |
30(37.5%) |
0.0027 |
1 |
0.95 |
| Females |
12(60%) |
8(40%) |
|
|
|
| Age group |
| <45 |
11(84.61%) |
2(15.38%) |
2.2343 |
1 |
0.134 |
| >45 |
51(58.62%) |
36(41.37%) |
|
|
|
| Stage of the disease |
| Early Stage ( I & II ) |
15(42.85%) |
20(57.14%) |
7.1718 |
1 |
0.007 |
| Advanced Stage (III & IV ) |
47(72.30%) |
18(27.69%) |
|
|
|
| Smoking status |
| Non Smoker |
17(56.66%) |
13(43.33%) |
0.24 |
1 |
0.6242 |
| Smokers |
45(64.28%) |
25(35.72) |
|
|
|
| Current Smoker |
23(82.14%) |
5(17.85%) |
5.25 |
1 |
0.02 |
| Ex Smoker |
22(52.38%) |
20(47.61%) |
|
|
|
| Smoking level ( pack year ) |
| Mild (<10) |
6(85.71%) |
1(14.28%) |
1.61 |
2 |
0.4471 |
| Moderate (< 40) |
20(60.60%) |
13(39.39%) |
|
|
|
| Heavy (> 40) |
19(63.33%) |
11(36.66%) |
|
|
|
| Histological type |
| ADC |
35(76.08%) |
11(23.91%) |
6.1105 |
1 |
0.0134 |
| SCC |
27(50%) |
27(50%) |
|
|
|
| Cytological type (ADC) |
| Well Differentiated |
6(77.77%) |
3(22.22%) |
0.66 |
2 |
0.7189 |
| Moderately Differentiated |
9(75%) |
3(25%) |
|
|
|
| Poorly Differentiated |
20(80%) |
5(20%) |
|
|
|
| Cytological type(SCC) |
| Well Differentiated |
14(46.66%) |
16(53.33%) |
2.8 |
2 |
0.2466 |
| Moderately Differentiated |
10(66.66%) |
5(33.33%) |
|
|
|
| Poorly Differentiated |
3(33.33%) |
6(66.66%) |
|
|
|
| Metastasis |
| Positive |
23(85.18%) |
4(14.81%) |
7.1447 |
1 |
0.0075 |
| Negative |
39(53.42%) |
34(46.57%) |
|
|
|
| Family history of any cancer |
| Significant (Positive) |
11(61.11%) |
7(38.88%) |
0.0332 |
1 |
0.8553 |
| Non Significant (Negative) |
51(62.19%) |
31(37.80%) |
|
|
|