Figure 2:(A) Scheme showing the Cell-SELEX procedure. The aptamer library is counter-selected against normal cells; the unbound aptamer library pool is collected and incubated with the target tumor cells; the aptamers bound on the tumor cells are released by heat denaturation. The iterations are continued for N times until the binding sequences are selected and identified. (B) Scheme showing Bead-based Aptamer selection process. The bead-based aptamer library is incubated with the protein mixture and the bound beads are sorted by Flow-Cytometry. The proteins are identified by MALDI-TOF mass spectrometry. Sequences on the beads can be determined by PCR, followed by sub-clonin