Drug
type

Polymer
type

Patients
number

Follow-up
(month)

Death
(%)

MI
(%)

ST
(%)

TLR
(%)

Late loss
(mm)

LEADERS49-52

Biolimus A9

PLA

857

9

2.6

 5.7

2.6

5.4

0.13

 

 

 

 

24

4.7

6.3

2.9

7.9

…..

 

 

 

 

48

9.2

8.3

3.4

10.3

…..

CUSTOM I59

Biolimus A9

PLA

30

24 / 8*

3.3

6.6

0

3.3

0.26

CUSTOM II60

Biolimus A9

PLA

100

12 / 6*

1.0

4.0

1.0

4.0

0.31

ISAR-TEST-353,54

Sirolimus

PLA

202

12 / 6-8*

2.0

1.5#

0.5

5.9

0.17

 

 

 

 

24

3.5

2.5#

0.5

8.4

…..

ISAR-TEST-455,56

Sirolimus

PLA

1299

12

4.7

4.3

1.0

8.8

…..

 

 

 

 

36

9.3

4.6##

1.2

13.9

…..

NEVO RES- I57

Sirolimus

PLGA

198

6

0.5

2.0

0

3.6

0.13

SERIES I61

Sirolimus

Mixed++

100

30 / 6*

3.0

1.0

1.0

4.0 (TVR)

0.09

FUTURE I62

Everolimus

PLA

27

12 / 6*

3.8

0

0

3.8

0.11

MAHOROBA63

Tacrolimus

PLGA

47

6

0

4.3

2.1+

23.4

0.99

COSTAR I64

Paclitaxel

PLGA

87

12

2.3

8.0

3.4

5.7

0.55-0.90

COSTAR II58

Paclitaxel

PLGA

989

8 / 9*

0.5

3.4

0.6

8.1 (TVR)

0.64

EUROSTAR65

Paclitaxel

PLGA

282

12 / 6*

2.1

3.9

1.1

3.1

0.28-0.40

EUROSTAR II66

Paclitaxel

PLGA

152

8

0

3.3

0

15.1

0.41

STELLIUM67

Paclitaxel

PLGA

37

6

0

0

0

2.7

0.19

JACTAX68

Paclitaxel

PLA

103

9

0

1.9

0

1.9

0.33

MI: Myocardial Infarction; ST: Definite or probable stent thrombosis defined in Academic Research Consortium; TLR: Target Lesion Revascularization; TVR: Target Vessel Revascularization; PLA: Polylactic Acid; PLGA: Polylactide-co-glycolic Acid; ++ Mixed polymer with PLLA (Poly L-Lactic acid), PLGA (50/50 Poly DL-Lactide-co-Glycolide) and PVP (Polyvinyl Pyrrolidone); * Clinical/angiographic follow-up; # Q wave MI only; ## Target vessel MI only; + Definite stent thrombosis only.
Table 1: Clinical outcomes of patients treated with biodegradable polymer DES.