Resources Purpose URL Ref
RRBSMAP A fast, accurate and user-friendly alignment tool for reduced representation bisulfite sequencing http://rrbsmap.computational-epigenetics.org/ [92]
BSMAP Ahole genome bisulfite sequence mapping http://code.google.com/p/bsmap/ [48]
BS Seeker Precise mapping for bisulfite sequencing http://pellegrini.mcdb.ucla.edu/BS_Seeker/BS_Seeker.html [46]
Bismark Map and determine the Methylation state of BS-Seq read http://www.bioinformatics.bbsrc.ac.uk/projects/bismark/ [47]
SOCS-B An alignment algorithm for bisulfite sequencing using the Applied Biosystems SOLiD System http://solidsoftwaretools.com/gf/project/socs/ [93]
BRAT Bisulfite-treated reads analysis tool http://compbio.cs.ucr.edu/brat/ [94]
BISMA Analysis of bisulfite Sequencing data from both unique and repetitive sequences http://biochem.jacobs-university.de/BDPC/BISMA/ [95]
BiQAnalyzerHT Locus-specific analysis of DNA methylation by high-throughput bisulfite sequencing http://biq-analyzer-ht.bioinf.mpi-inf.mpg.de/ [49]
CpGviewer Sequence analysis and editing for bisulphite genomic sequencing projects http://xserve1.leeds.ac.uk/~iancarr/cpgviewer [50]
CpG PatternFinder Windows-based program for bisulphite DNA - [52]
CyMATE Bisulphite-based analysis of plant genomic DNA http://www.gmi.oeaw.ac.at/CyMATE [51]
GenomeStudio Software Analyzing data generated from Illumina assays - -
MethMarker Design, optimize and validate DNA methylation biomarkers for a given DMR http://methmarker.mpi-inf.mpg.de/ [96]
BDPC Bisulfite sequencing Data methylation analysis. http://biochem.jacobs-university.de/BDPC [97]
MethylCoder Software pipeline for bisulte-treated sequences https://github.com/brentp/methylcode [98]
QUMA Quantification tool for methylation analysis http://quma.cdb.riken.jp/ [53]
CyMATE ,Cytosine Methylation Analysis Tool for Everyone; BSMAP, Bisulphite Sequence Mapping Program, BISMA, Bisulfite Sequencing DNA Methylation Analysis; BRAT,bisulte-treated reads analysis tool; DMR, differentially methylated DNA region; QUMA, Quantification Tool For Methylation Analysis.
Table 4: Analysis of bisulfite sequencing data with computational tools.