Thrombophilic defect Recurrent pregnancy loss before 13 weeks (95% CI) Non-recurrent pregnancy loss (95% CI) Non-recurrent pregnancy loss  after 19 weeks (95% CI)
Antithrombin deficiency 0.88 (0.17-4.48) 1.54 (0.97-2.45) 7.63 (0.30-196.36)*
Protein C deficiency 1.57 (0.23-10.54) 1.41 (0.96-2.97) 3.05 (0.24-38.51)*
Protein S deficiency 14.72 (0.99-218) 7.39 (1.28-42.83) 20.09 (3.70-109-15)*
Factor V Leiden 2.01/1.91*
(1.13–3.58)/(1.01-3.61)*
1.73 (1.18-2.54) 3.26/2.06*
(1.82-5.83)/(1.10-3.86)*
Prothrombin G20210A 2.05/2.70*
(1.18-3.54)/(1.37-5.35)*
2.32 (1.12-4.79) 2.30/2.66*
(1.09-4.87)/(1.28-5.53)*
Table 2: Relative risk for relative fetal loss associated with hereditary thrombophilic defects according to ref. [21] and [22]*.