Pre-ECMO             Increasing Age             Low body weight             Duration of ventilator support prior to ECMO             pH<7.18             Hispanic/Asian race             PaCO2 > 70 mmHg Complications while on ECMO             Circuit/pump complications (rupture)             Stroke/seizures             Gastrointestinal bleeding             Pulmonary hemorrhage             Use of or need for neuromuscular blockage             pH<7.2 or pH>7.6             CPR on ECMO             Inotropic medications             New infections             Arrhythmias

Adapted from Brogan TV, et al. Intensive Care Med. 2009 Dec;35(12):2105-14) 1Interestingly, cardiac arrest prior to ECMO was not associated with a significantly worse outcome in the univariate model analysis (p=0.28)

Table 5: Predictors of Poor Outcomes of ECMO Support.