(A) Western blot of MMP-1 expression in dermal fibroblasts after 24 hours in either 1= KLC conditioned medium from day 28 of cell transdifferentiation 2= Dulbecco’s modified Eagle medium + 2% FBS(negative control) 3= empty 4= dermal fibroblasts treated with recombinant stratifin (positive control) (B) Densitometry analysis of MMP-1/ β-actin ratio. (n=4)

Figure 2: Matrix metalloproteinase-1 (MMP-1) expression in dermal fibroblasts treated with KLC conditioned medium.