| |
RCT NO. 1 – EST vs. EPCS |
RCT NO. 2 – EPCS vs. TIPS |
| |
EST (n = 106) |
EPCS (n = 105) |
|
EPCS (n = 76) |
TIPS (n = 78) |
|
| Hours |
Median/Mean |
Range |
Median/Mean |
Range |
P Value |
Median/Mean |
Range |
Median/Mean |
Range |
P Value |
| Onset bleeding to study entry |
12/19.8 |
0-144 |
16/19 |
0-95 |
0.30 |
20/25.4 |
0-112 |
17/24.2 |
0.5-84 |
0.56 |
| Onset bleeding to primary therapy |
15/23.3 |
3-147 |
19/21.5 |
2.6-100 |
0.056 |
27.5/35.9 |
8-131.7 |
34.2/39.0 |
11.1-99.4 |
0.08 |
Study entry to primary therapy
n >8 h
% >8 h |
2.5/3.1
0
0 |
0.8-8 |
3.4/4.4
3
2.9 |
1.4-24.3 |
<0.001* |
9.5/10.2
3
3.9 |
2-30.1 |
14.6/14.7
76 (97)
68 (87) |
2.3-38.4 |
<0.001*
1.0
0.5 |
Transfer patients, n (%)
Onset of bleeding to entry in referring hospital
Entry into referring hospital to study entry |
71 (67)
4.05/10.4
7.2/11.8 |
0-127
1.5-53 |
80 (76)
3.75/9.7
8.4/11.6 |
0-83.6
0-53 |
0.17
0.92
0.56 |
63 (83)
6.3/11.9
13.0/18.4 |
0-120
2.2-110 |
68 (87)
5.7/9.8
10.5/16.4 |
0-62
2.6-65.3 |
0.5
0.72
0.42 |
Last observation of bleeding to study entry
≤4 h, % of group
>4 h, % of group |
0/1.9
84
16 |
0-32 |
0/2.5
84
16 |
0-30 |
0.76
0.94
1.00 |
0/1.6
67 (88)
9 (12) |
0-32 |
0/3.6
63 (81)
15 (19) |
0-84 |
0.35
0.27 |
*Statistically significant difference