Figure 4: Blood flow to the treated tumor area is transiently reduced. - N1- S1-Luc tumors were initiated and treated as describe in the legend to Figure 1. Before, immediately after and 7 days after treatment, Liver blood flow in the treated area was determine by laser Doppler imaging (Moor LDLS laser Doppler imager) and expressed as perfusion units. The data are expressed as percent of blood flow immediately before treatment. The * indicates the change is significant compare with pre-treatment (one way-ANOVA, p<0.01); # indicates the two post-treatment groups are statistically different (two way- ANOVA, p<0.001). The designation 1000X indicates that tumors were pulsed 1000 times.