GFs Carriers Species Defect models References BMP-2 DMB New Zealand Rabbit Mandibular [12] ACS Beagle dog Alveolar periodontal [170] ACS + DMB Mongrel dog Alveolar ridge augmentation [13] ACS Human Alveolar ridge augmentation [14] ACS Human Sinus floor augmentation [15] BMP-7 Hydroxyapatite Baboons Calvarial [16] Collagen Beagle dog Periodontal [17] --- Mongrel dog Extraction site [18] Collagen Human Sinus augmentation [19] PDGF DMB + e-PTFE Beagle dog Alveolar periodontal [24] DMB + e-PTFE Mongrel dog Alveolar periodontal [25] DMB Human Alveolar periodontal [26] β-TCP Human Alveolar periodontal [23] EMD --- Cementoblasts (in vitro) --- [31] --- Pre-osteoblasts (in vitro) --- [32] --- Human Alveolar periodontal [33] GDF-5 Collagen Mouse Calvarial [35] β-TCP Beagle dog Alveolar periodontal [36] Particulated bone/block bone Beagle dog Mandibular [37] β-TCP Human Alveolar periodontal [38] Absorbable Collagen Sponges (ACS); Bone Morphogenetic Protein 2 (BMP-2); β-tricalcium phosphate (β-TCP); demineralized/mineralized bone matrix (DMB); Enamel- Matrix Derivatives (EMD); expanded polytetrafluoroethylene (e-PTFE); Growth/Differentiation Factor-5 (GDF-5); and platelet derived growth factor (PDGF).

Table 1: Summary of GF studies for oral and craniofacial regeneration.