Item (pg/ml) |
Control
n=20 |
All RA patients
n=94 |
Early RA patients
n=22 |
Late RA patients
n=41 |
IL-1-ser |
1,65±0,03 |
0,86±0,17 |
0,25 ± 0,30* |
0,96 ± 0,20*◊ |
IL-6-ser |
2,47±0,03 |
60,22±3,40 * |
7,32 ± 4,33 |
104,55 ±41,20*◊ |
IL-10-ser |
0,21±0,02 |
0,50±0,23 |
0,25 ± 0,23 |
0,45 ± 0,39 |
TNF-ser |
2,17±0,07 |
3,69±1,18 |
3,97 ± 1,93 |
3,06 ± 1,46 |
IL-1-sin |
1,95±0,91 |
10,06±2,28* |
13,87 ± 2,60* |
0,60 ± 0,40 *◊ |
IL-6-sin |
3,48±1,12 |
1431,77±110,96* |
1505,00±182,04* |
1745,00±35,53* |
IL-10-sin |
1,11±1,02 |
7,26±1,18* |
4,30 ± 2,60 |
10,82 ± 5,17*◊ |
TNF-sin |
4,12±2,03 |
150,59±15,61* |
101,00 ± 80,00* |
158,21 ± 8,05* |
Note: n — number of patients in each group. * — differences from the control were significant at р<0.05 |