Author(s)

Biological material

Proteomic approach

Differently expressed proteins

Rottoli P et al. [9]

BALF

2-DE

Protease, anti-protease
Coagulation system
Cytokines
Anti-oxidant proteins
Calcium binding proteins

Rottoli P et al. [10]

BALF

2-DE

Transferrin
Immunoglobulin(s)
Complement protein

Fietta AM et al. [18]

BALF

2DE MALDI-TOF HPLC-MS

Glutathione S-transferase P
Cystatin SN

Bargagli E et al. [22]

BALF

2-DE

Calgranulin B (S100A9)

De Santis M et al. [23]

BALF

reverse phase HPLC coupled to quadrupole ion-trap MS -ESI

Thymosins β

Bargagli E et al. [28]

BALF

2-DE, ELISA

Macrophage Inhibitory Factor

Shirahama R et al. [19]

BALF

2-DE MALDI-TOF MS

α2 macroglobulin
α1 antitripsin
Pulmonary surfactant protein A
Heat shock protein
Glutathione S-transferase P

Bogatkevich GS et al. [29]

fibroblasts from BALF

2-DE/MS

Vimentin
Tropomyosin
Actin
Disulfide isomerase
Glutathione S-transferase

Table 1: Proteomic Studies on Bronchoalveolar Lavage Fluid from Patients with Ssc and Pulmonary Involvement.