(a) Histological section of cartilage repair tissue within the knee joint of
a minipig model 6 months after treatment by MFX. The repair tissue is
characterized by excessive outgrowth of the subchondral bone tissue and
overlying fibrocartilaginous tissue.(b) High magnification of the repair tissue in a minipig model 6 weeks following MFX. Repair cells of deeper zones differentiate into hypertrophic chondrocytes prior to be replaced by endochondral ossification (Toluidin blue staining).
