Figure 4: Characterisation of normal and OA-derived cartilage stem cells. [A] Representative growth curves of a normal and OA-derived stem cell line. [B] Telomere length assayed by Single Telomere End Length Analysis (STELA) in stem cell lines and full-depth chondrocyte populations. STELA reveals both stem cell lines and full-depth chondrocytes undergo telomere erosion [C]. It is interesting to note a subpopulation of cells in the stem cell line show a larger distribution which is increasing with time in culture (arrowed).