Physiological Characteristics:
Neurotransmitters
Glutamate
GABA
Glycine
Substance P
Neuropeptide Y
Serotonin (5-HT)
Kainate
Receptors:
mGluR1, mGluR2, & mGluR3
NRB1 & NRB2 A/B
GABAA/B
P2X3-7
TRPA1
TRPV1
NK1 & NK2
AMPA
KA
Neuromodulators:
Calcitonin gene-related peptide (CGRP)
Brain-derived neurotrophic factor
(BDNF)
Neurokinin-1
Purinergic
Nitric Oxide (NO)
Prostaglandins
Table 1: Mediators of sensitization in both the VBSNC and the spinal cord.