Characteristics

All patients
(n-16)

HPV positive
(n=8)

HPV negative
(n=8)

p-value

Age
                Mean
                Range

72.2
52-86

76.3
53-86

68.0
52-81

0.38

Sex
                Male
                Female

10
6

5
3

5
3

n/a

TNM stage
                I/II
                III
                IV

0
6
10

0
4
4

0
2
6

0.36

Nodal involvement
                Positive
                Negative

8
8

4
4

4
4

n/a

Tumor type
                Primary
                Recurrent

9
7

5
3

4
4

0.36

XRT
                Yes
                No

13
3

8
0

5
3

0.2

Number of Recurrences
                0
                1
                2
                3

6
6
2
2

5
2
1
0

1
4
1
2

*0.001

Number of Surgeries
                1
                2
                ³3

8
6
2

6
2
0

2
4
2

*0.003

Survival
                Yes
                No

14
2

7
1

7
1

n/a

Alcohol
                Yes
                No
                Not recorded

8
7
1

3
4
1

5
3
0

0.62

Smoking
                >1PPD
                no or <lPPD
                Not recorded

10
5
1

5
2
1

5
3
0

1

Abbreviations: HPV: human papillomavirus. XRT: radiation therapy, PPD: pack per day
Table 3: Characteristics of Patients with HNSCC.