Variable Coefficient p-value OR & 95% CI Diffuse Y vs N 0.52 0.7093 1.68 (0.11, 25.62) Focal Y vs N 3.12 0.0780 22.55 (0.71,721.43) SUVm 0.11 0.8572 1.11 (0.35, 3.49) AvSUV -0.82 0.2902 0.44 (0.10, 2.01) SUV/MBP -0.28 0.4669 0.50 (0.07, 3.75)

Table 4: Full Logistic model on BM pathology diagnosis result based on semi-parametric variables and BM uptake pattern with Patchy as the reference group for uptake pattern.