OMT Residues MsCOMT Asp206 Gly208 Asp231 Leu232 Asp251 Met252 Lys265 Trp271 NtOMT2 Asp208 Gly210 Asp233 Leu234 Asp253 Met254 Lys267 Trp273

Table 4: Residues in NtOMT2 and MsCOMT neighbouring the AdoMet binding site.