ACh (n=1546) ER (n=1114) adding ACh after ER test (n=240) Procedures         Direct current 5 (0.32%) 2 (0.18%) 0   Cardiac massage 8 (0.52%) 1 (0.09%) 0   Thump version 5 (0.32%) 1 (0.09%) 0   Surgical drainage 1 (0.06%) 0 0   Cessation of tests 1 (0.06%) 2 (0.18%) 0         Administration         Noradrenaline (intra aorta) 4 (0.26%) 0 0   Anti arrhythmic agents (VT/VF) 1 (0.06%) 0 0   Anti arrhythmic agents (Paf) 82 (5.3%) 0 8 (3.3%)   Nitrate (intra coronary) before another vessel 31 (2.0%)** 76 (6.8%) 6 (2.5%)*

(ACh: acetylcholine, ER: ergonovine, VT: ventricular tachycardia, VF: ventricular fibrillation, Paf: paroxysmal atrial fibrillation, *p<0.05, **p<0.01 vs. ER)

Table 2: Procedures and administrations for major and minor complications.