Drug Designing: Open Access
Open Access

International Conference and Expo on Drug Discovery & Designing

August 11-13, 2015 Frankfurt, Germany

Posters-Accepted Abstracts

• Mechanistic study of NVP-CGM097: A potent, selective and species specific inhibitor of p53-Mdm2

  Marie Therese Valat

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• Emodin dissipates tonic tension through suppressing PKCδ-mediated calcium sensitization in blood vessel

  Jin-Ho Chung, J H Kwon and K Y Kim

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• Functional variation of soluble polyphenols tannins in apple oak and pomegranate peels as anticancer therapeutic drug

  ChrowKhurshid and Osamah Ahmed

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• Dual targeting of 83-14 monoclonal antibody- and anti-epithelial growth factor receptor-grafted solid lipid nanoparticles for glioblastoma multiforme therapy

  Chia-Hao Lee

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• New features of intracellular parasite elimination in the presence of new anti-proliferative compounds: New insights to drug development

  Laís Pessanha de Carvalho

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• Regulation of tailoring biosynthetic genes of the aur1 cluster for the Angucycline antibiotic auricin in Streptomyces aureofaciens CCM 3239

  Carmen Bekeová, Mingyar E, Novakova R, Feckova L and Kormanec J

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• A theoretical study on the effect of N-methylation of amino acids (Ac-X-OMe) on their electronic structure and ADMET properties

  Shah Md. Abdur Rauf, Per I Arvidsson, Thavendran Govender, Glenn E M Maguire, Hendrik G Kruger and Bahareh Honarparvar

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• Designed, synthesized and molecular modeling studies of a novel group of 5-substituted (1-benzyl- 2-(methylsulfonyl)-1-H-imidazole) as selective cyclooxygenase-2 inhibitors

  Azin Kiani, Sayyed Abbas Tabatabai and Elham Rezaee

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• Immunohistochemical study of the effect of chamomile extract on 5- fluorouracil induced intestinal mucositis in albino rats

  Ali Sultan Al-Refai

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• Effect of chamomile extract on the tongue of chemotherapy treated albino rats (histopathological and immunohistochemical study)

  Ameera Kamal Khalil, Ali Sultan Al-Refai and Othman A Omar

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• The adjunctive use of locally delivered metformin as mucoadhesive slow releasing multiple layer film in the management of chronic periodontitis

  Ragwa Mohamed Farid1, Abeer Ahmed Kassem2, 3, Doaa Ahmed Elsayed Issa4, 3 and Gehan Sherif Kotry3

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• Development and characterization of a controlled-release Ciprofloxacin hydrochloride drug delivery system

  Samar Zuhair Alshawwa

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• Preparation and evaluation of mucoadhesive Resveratrol microbeads using thiolated alginate for intrapocket delivery

  Abeer Ahmed Kassem1, 2, Ragwa Mohamed Farid3, Doaa Ahmed Elsayed Issa4, 2, Doaa Said Khalil5, Mona YehiaAbd-El-Razzak6, Hussein Ibrahim Saudi6, Heba Mohamed Eltokhey6 and EnasArafa El-zamarany6

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• Targeting the Notch signaling pathways of hepatocarcinoma and glioblastoma multiform using ultra small iron oxide nanoparticles conjugated gamma secretase inhibitor

  Anamaria Orza

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• Expanding the scope of fragment screening libraries: Thinking in 3D

  Angelo Pugliese

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• A design of experiment study to engineer the properties of chitosan nanoparticles as matrix to sustain drug release across orally disintegrating tablets

  Arwa matoug-elwerfalli 1, Amr ElShaer *1

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• Amplifying the role of collaboration globally for neglected and commercial disease drug discovery

  Barbara Holtz, Charlie Weatherall and Barry Bunin

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• Design, homology modeling, docking studies and microwave-assisted synthesis of some novel triazolothienopyrimidines as possible antagonosts of A3 adenosine receptors

  Rajwinder K1 and Raghuram Rao A2

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• CREB binding protein (CBP) inhibition and target engagement

  Eugene Piatnitski Chekler

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• Synthesis of novel N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl) piperidine-4- carboxamide derivatives as potential antiangiogenic and DNA cleavage agents

  Vinaya K

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• Computational simulation of the effect of quantum chemical parameters on the molecular docking of HMG-CoA reductase drugs

  Faten Mahmoud Ahmed Atlam

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• Comparative study of sitagliptin analysis on halogenated stationary phases in pharmaceutical formulation

  Hebatallah A Wagdy1 and Hassan Y Aboul-Enein2

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• Toward full understanding of the EPR effect in primary and metastatic tumor, and issues of heterogeneity: For tumor selective delivery and imaging using nano-particles

  Hiroshi Maeda, Jun Fang, Kenji Tsukigawa and Hideaki Nakamura

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• Lipophilic phenoxazines as potent and specific inhibitors of Akt signaling in rhabdomyosarcoma cells

  Kuntebommanahalli N Thimmaiah1, B T Sridhar2 and Kanchugarakoppalu S Rangappa3

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• Small tri-peptide plays a leading role in promote bone marrow stem cell differentiation into isletlike insulin positive cells

  Luguang Luo, Zhengke Wang, Fang Xiong and John Z Luo

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• Determination of the antioxidant and cytotoxic activities of the leaves of artocarpus odoratissimusblanco (Moraceae)

  Mary Camille Castillo, Ocat, M N; Aquino, J A E; Canto, G P B; Capuno, B M P; Cruz, A T F; Din, G C F; Lucero, D G O; Morales, R V D; Pajarillo, J D L; Pesigan, J M A; Yap, J A C, Yap, P M M Kua, M F

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• Developing VLP (Virus like particle) based nano-particulate HPV (Human papillomavirus) vaccine for cervical cancer

  Mohammad Nasir Uddin

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• Chlorogenic acid: A potential molecule with β-lactamase inhibitory activity against drug resistant bacteria

  Pallavi Sahare and Archana Moon

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• Herbal medicine vital role in women’s health: A perspective review

  R Ramasubramania Raja

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• Drug discovery efforts mirror the proverbial hyper cycle: What’s next?

  Rathnam Chaguturu

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• Selection of best calibration model during bioanalytical method validation

  Sandeep Sonawane

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• Development of 5-fluorouracil enteric -coated nanoparticles for sustained and localized release and their in vitro characterization for treatment of colorectal cancer

  Shashank Tummala and M N Satish Kumar

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• Geraniin extracted from the nephelium lappaceum (rambutan) rind inhibits dengue virus type-2

  Siti Aisyah Abdul Ahmad, Uma Palanisamy, Bimo A Tejo and Sharifah Syed Hassan

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• Preclinical drug discovery with patient-specific engineered heart tissues

  Tetsuro Wakatsuki

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• Potential co-targets of isoniazid from protein-protein interaction network analysis

  Tilahun Melak and Sunita Gakkhar

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• A new broad spectrum herbal drug that cures human candidiasis

  Udai Pratap Singh, Mandavi Singh and Ravi Vikram Singh

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• Cucurbitane derived terpenoidal moieties from under-utilised cucurbits as probable medicinal leads

  Ujjwal Kaushik1, M Ali2 and Vidhu Aeri2

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• Current progress in structure-based rational drug design marks a new mindset in drug discovery

  Valère Lounnas

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• Spin-labelled 1-ethyl-1-nitrosourea prevents Doxorubicin and Bleomycin-induced oxidative stress in lungs, hearts and kidneys of tumour-bearing mice

  Wessam El-Refaie

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