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Journal of Bioprocessing & Biotechniques

ISSN: 2155-9821

Open Access

Current Issue

Advances in Bioprocess and genetic Engineering (2021)

    Research Article Pages: 1 - 3

    Comparative Anti-Microbial Activity Analysis of Ixora coccinea and Datura metel

    Spoornima Krishnan*, M Priya, H Jaya Ganga, V Malliga and K Yaazhini

    DOI: 10.37421/2155-9821.2021.11.401

    The plants are rich in anti-microbial agents for their anti-microbial activity. In this study, the powdered leaves extracts of Ixora coccinea and Datura metel were macerated and extracted with solvents in acetone, methanol and iso-propanol. The study was done to evaluate the anti-microbial property of leaf extracts of Ixora coccinea and Datura metel against the bacterial strain of Escherichia coli and Staphylococcus aureus by agar well diffusion method. From the antimicrobial activity assay, the best zone of inhibition formation li whereas Datura metel had shown good anti-bacterial activity against Staph of 11.8 ± 0.64 mm was observed in the case of Ixora coccinea against the bacterial strain of Escherichia coli Staphylococcus aureus by the inhibition zone formation of 15.3 ± 0.27 mm.

    Mini Review Pages: 1 - 4

    Ezrin Peptide Therapy: A Potential Treatment for COVID

    Rupert D Holms* and Ravshan I Ataullakhanov

    DOI: 10.37421/2155-9821.2021.11.403

    Ezrin Peptide Therapy was invented in London and developed in Moscow over the previous three decades. Synthetic 14 amino acid peptides that mimic a receptor site in human ezrin, inhibit inflammation and amplify adaptive anti-viral immunity. Human Ezrin Peptide One (HEP1, Gepon) was registered for human use in the Russian Federation in 2001. The successful treatment with ezrin peptides of acute viral respiratory infection with pneumonia complications, led to testing of ezrin peptides as a potential COVID therapy. RepG3, a derivative peptide of HEP1, which has double the IL-6-expression inhibition activity, is being developed as a therapy for COVID and may also help to prevent SARS-CoV-2 re-infection.

    Bioprocessing (2021)

      Editorial Note Pages: 1 - 1

      Editorial Note for journal of Bioprocessing & Biotechniques

      Y.N. SAI CHANDRA

      Journal of Bioprocessing and Biotechniques commemorates its decade long service to the scientific community by consistently publishing peer-reviewed articles and tracking the progress and significant advancements in the field of biosensors. Ever since its inception in the year 2011, in addition to regular issue releases on a quarterly basis, this transdisciplinary journal is also releasing special issues and conference proceedings from time to time, thus comprehensively covering a wide range of topics and emerging challenges in bio techniques and bio processing. The journal focuses on application oriented research on biological, biochemical, biophysical and electronic principles with biological, biomedical and environmental relevance and utility. In this issue some of the recent and impactful research articles that were published by the journal will be discussed. 

      Research Pages: 1 - 8

      Investigation and Reaction Kinetics Modeling of Biomass Formation

      Rebecca Faschian, Steven Minden and Ralf Portner*

      Lactic acid bacteria (LAB) like Lactococcus lactis ssp. lactis are used in food industry as well as for production of bacteriocins and optically pure lactic acid. Fixed-bed processes are highly productive but mathematical description is often complex. The aim of this work was to establish a mathematica model for process design. Biomass formation, lactose consumption and lactate production during start-up of fixed-bed cultures with immobilized L. lactis was investigated experimentally and described by a reaction kinetics model. Appropriate modeling and simulation of fixed-bed processes require biomass data. Therefore, a low-volume multiple fixed-bed reactor system (Multiferm) was used to investigate biomass formation of a L. lactis strain during the start-up phase of fixed-bed cultivation. The generation of data in parallel experiments was fast and easily compared to larger single reactor systems. Biomass data obtained from both fractions, retained and free suspended biomass, was used for modeling and simulation, together with data for lactose and lactate. The underlying Luedeking-Piret-like model structure was developed based on the results from suspension cultivations with the same strain. The fixed-bed system was described as perfusion culture with cell retention. For this, merely four additional parameters had to be defined to extend the suspension model to fixed-bed cultures. Experimental trends and steady states of both biomass fractions besides substrate and product could be described very well. Thus, this model could be used for process layout during process development..

      Research Pages: 1 - 7

      Antioxidants, Free Radical Scavengers, DNA Protection and Antimicrobial Activities of The Plant Natural Products

      Khalid S. Abdel-lateif1,4*, Ibrahim A. Maghrabi2,4 and Hany A. Eldeab3,4

      The plant natural products are chemical compounds or substances produced by plants and have different activities or functions. These products exhibited several important biological activities such as antimicrobial, anti-allergic, antiinflammatory, antioxidant and free radical scavenging due to their rich content of compounds as polyphenols. The highly reactive oxygen species (ROS) generated during the metabolism can cause oxidative damage for biomolecules as RNA and DNA, resulting in cell cellular damage and death. It was shown that the antioxidant activities found in plant natural products could provide protective effects via inhibiting DNA oxidative damage. This review highlights some of important roles of the plant natural products as antioxidants and as antimicrobials.

      Research Pages: 1 - 8

      Response Surface Methodology and Evaluation of its Antitumor Activity

      Zhan Xiao-ri1,2, Xu Li-li1, Xiong Feng3, Li Xiao-lin2, Yu Chun-na1, Xie Tian2 and Li Xia3*

      This work established a microwave-assisted procedure for polysaccharide extraction from Polygonatum odoratum. Response surface methodology was used to optimize microwave-assisted extraction parameters (extraction temperature, water-to-raw material ratio, microwave power, and extraction time) by implementing a three-level, fourvariable Box–Behnken experimental design in a single-factor investigation. Three-dimensional response surfaces were plotted by Design-Expert, and result indicated the absence of interaction effects of extraction temperature and microwave power. A polysaccharide yield of approximately 17.49% was obtained under the following optimized conditions: temperature of 57°C, microwave power of 300 W, extraction time of 10 min, and water-to-raw material ratio of 23:1. The results of preliminary in vitro antitumor activity tests showed that polysaccharides derived from P. odoratum could inhibit growth of A549 cells in a dose-dependent manner. Moreover, 4-400 μg/mL of these polysaccharides exerted no significant cytotoxicity to Panc-1 cells.

      Research Pages: 1 - 3

      Leading Health Indicator is Infant Mortality

      Ariana Vitale, Anita Mandal and Prabir K Mandal*

      The purpose of this research was to study infant mortality and their rates in Duval County, Florida. Infant mortality rate is the estimate of infant deaths per 1,000 live births. The U.S. Infant Mortality Rate (IMR) currently ranks 27th among industrialized countries, with wide and persistent disparities by race, socioeconomic status, and geography. The objective of this research was to study infant mortality rates in each zip code in Duval County along with demographic information such as poverty, household income, prenatal care, and education. An analysis of the data collected was then used to establish whether there is a correlation between as poverty, household income, prenatal care, and education with infant mortality rates in zip codes with the highest and lowest infant mortality rates. The data for this research was gathered through the Florida Health department and nefloridacounts.org. The infant mortality rates and demographic information was sourced from the year 2014.

      Biomolecular Engineering (2021)

        Perspective Pages: 1 - 2

        The New Innovation Shows Huge Guarantee of Harvests That are More Bug Safe and Nutritious

        Sushantika Killer

        Science is level headed and worth free, as it ought to be. It isn't the researcher's undertaking to make or change social, monetary, or political strategy. Target science is driven by interest in the normal world, mission of the utilizing establishment, and requests of the subsidizing that empower the examination. Researchers endeavor to comprehend and clarify the normal world, and innovation applies logical discoveries to the world. Public and logical discussions about biotechnology regularly seem, by all accounts, to be overwhelmed by total inverse perspectives.

        Commentary Pages: 1 - 2

        A Brief note on Bioethanol Production

        Abdul Akhtar*

        Bioethanol is created principally from sugar and starch sourced from harvests, for example, sugar stick, wheat, and corn, which have a high convergence of sugar. Nonetheless, because these yields are additionally significant food sources, bioethanol created from them can fundamentally affect food costs and food security. Interestingly lignocellulosic biomass, buildups from wood or devoted energy crops is an option because there is no contest with food and creature feed creation. These materials are additionally less expensive than original biomass. Moreover, the utilization of lignocellulosic materials as fluid fills can support lessening ozone-depleting substance outflows. Lignocellulosic biomass is the wellspring of hexose and pentose sugars and is used in the production of bioethanol. In contrast to original biomass, the cellulose in the cell division of second-generation lignocellulosic substrates is encased in a hemicellulose and lignin network, making cellulose availability a key challenge in bioethanol production from such sources.

        Editorial Pages: 1 - 2

        Production of Bioethanol Using Waste of Food Products

        Mayuri Halder*

        The source of ethanol is corn and other sugar-based crops, which has increased the pressure on food industries. The crops produced for consumption are now utilized in the formation of ethanol. The food processing industry is the second most waste-producing industry after household sewage. The solid and liquid waste released from the fruit industries can pose a vital contributor to land pollution. Processing of fruits can yield residues, which are in the form of pods, peels, pulp, stones, and seeds. Disposal of these residues without processing in landfills can further aggravate the situation by causing environmental pollution.

        Research Article Pages: 1 - 4

        A Brief Review on Bio-Enzymes

        Md.Abdul Akhtar

        In nature, there is harmony between microbes and non microorganisms. For example, the non-pathogenic microscopic organisms like nitrogen-fixing microorganisms ,eg.spirulina resides in the deep roots of the plant; lactobacillus in the milk helps in the change of milk to curd. There is a gigantic number of good microscopic organisms present in the human gut, which helps in food processing and assimilation. In this way, to disinfect our air with synthetic cleaners, we are possibly annihilating the non-pathogenic microorganisms too from the climate. Besides, these synthetic cleaners takes out sewage from the houses as polluted water, and contaminates the water bodies, air, and make the soil unfertile. For example, the clothing cleansers contain phosphate and nonbiodegradable branch-affixed alkyl sulphonates, which causes relentless froth

        Editorial Pages: 1 - 2

        A Brief Note on Understanding the Mitochondrial Function in Cellular Activities

        Himani Prasad*

        Mitochondria are extraordinary compartments (organelles) in our cells that are most popular for their job as forces to be reckoned with, as they breakdown food particles and turn out ATP, an atomic fuel for the remainder of the cell. Nonetheless, they complete numerous other significant organic cycles and are integral to the right working of the human cell. The mitochondrion has two films: an external layer, which is permeable for most atoms, and an inward layer, which is firmly fixed and has invaginations called cristae. Mitochondria can wire and separation and structure broad organizations in the cell that are exceptionally powerfu

        Perspective Pages: 1 - 1

        A Brief Note on Bioprocessing Techniques

        Santanu Kumar*

        Bioprocess technology is the modern use of natural cycles, including living cells and their components into substrates. The significant benefits of bioprocesses over conventional synthetic cycles are that they require gentle response conditions, are more explicit and proficient, and produce inexhaustible results (biomass). The advancement of recombinant DNA innovation has extended and expanded the capability of bioprocesses. A bioprocess is any interaction that utilizations complete living cells or their parts (e.g., microscopic organisms, catalysts, chloroplast) to acquire wanted items. This interaction is usually alluded to as Fermentation.

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Google Scholar citation report
Citations: 3351

Journal of Bioprocessing & Biotechniques received 3351 citations as per Google Scholar report

Journal of Bioprocessing & Biotechniques peer review process verified at publons

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