Subjects No. of cases GSH (mg/dl) GST (IU/L) GPx (nmol/min/ml)
Healthy controls 30 3.96±1.18 1.81±1.21 24.22±3.53
Breast cancer patients
Stage II before chemotherapy 30 2.84±0.42e 12.58±3.90a 51.79±8.55a
Stage II after first cycle of chemotherapy 30 1.89±0.40ab 5.33±1.54ab 36.53±5.62ab
Stage III before chemotherapy 30 2.33±0.82ab 13.01±3.79ab 69.11±16.50ab
Stage III after first cycle chemotherapy 30 1.79±0.53ac 5.96±1.38ac 50.31±13.07ac
The data was expressed as Mean ± SD.
a P<0.0001 Significant when compared to healthy controls.
e P=0.0004 Significant when compared to healthy controls.
b P<0.0001 Significant when compared to stage II breast cancer patients before chemotherapy.
c P<0.0001 Significant when compared to stage III breast cancer patients before chemotherapy.
Table 2: Depict serum levels of reduced glutathione (GSH), glutathione-s-transferase (GST) and glutathione peroxidase (GPx) in healthy controls and post-operative breast cancer patients before and after chemotherapy.