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Figure 4: (A) Paraquat sensitivity assay: PE significantly improves the survival of N2 wild type C. elegans under normal as well as oxidative stressed (paraquat exposure) environment. (B) Survival curve of N2 wild type and hsf-1 (RNAi knockout) C. elegans under control and PE treated conditions. Since PE-exposure does not increase the mean life span of hsf-1 (RNAi knockout), PE’s life expanding action in proposed to be dependent on HSF-1 (heat shock factor). (Figure 4A and 4B are adapted from Sonani et al. [6] and Sonani et al. [40], respectively) |